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What is Rybelsus (oral Semaglutide)?
Buy Rybelsus @ £185 per box – is the brand name for a new oral medication used in the treatment of type 2 diabetes. The generic name is Semaglutide and this is the same molecule that has been previously only been available as a once-weekly injection called Ozempic.
Ozempic and Victoza (Liraglutide) are small proteins called peptides and normally these are broken down in the gut and no longer work. The major innovation with Rybelsus is the engineering to allow it to be taken orally, not be broken down, and yet still be effective.
The normal maximum dose of injected Ozempic is 1mg whereas the maximum dose of Rybelsus is 14mg. The different doses suggest that a lot of Rybelsus is still broken down in the gut before being absorbed.
What is the dose of Rybelsus (Semaglutide)?
Rybelsus comes in three different dosages;
What is the Rybelsus starting dose
The starting dose of Rybelsus is 3mg once daily for the first month (30 days). After this time, and if the person is able to tolerate the medication, the dose should be increased to 7mg daily.
If blood sugars are still high, the Rybelsus dose may be increased to 14mg once daily after at least 30 days on the 7mg dose. To avoid confusion it is not recommended that two 7mg Rybelsus tablets be taken to achieve a 14mg dose and instead the 14mg single tablet be taken.
Semaglutide is the synthetic version of a naturally occurring human hormone, called Glucagon-like peptide 1 or GLP-1 that has been modified so that it is less likely to be broken down and therefore has a longer duration of action.
Whether you have diabetes, or you don’t have diabetes, we all make GLP-1. It has become clear that GLP-1 is a really important hormone to help us regulate our blood sugar levels and probably our appetite and weight.
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